Both vaginal creams used for bacterial vaginosis, flagyl and clindamycin, have cure rates of 50-95 but relapse rates are 34 to 49 four weeks later.
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Many antibioticsincluding clindamycinmay cause overgrowth of dangerous bacteria in the large intestineThis may cause mild diarrhea or may cause a life-threatening condition called colitisinflammation of the large intestineClindamycin is more likely to cause this type of infection than many other antibioticsso it should only be used to treat serious infections that cannot be treated by other antibioticsTell your doctor if you have or have ever had colitis or other conditions that affect your stomach or intestines.
Clindamycin has been shown to have neuromuscular blocking properties that may enhance the action of other neuromuscular blocking agentsThereforeit should be used with caution in patients receiving such agents.
For anaerobic bacteriathe susceptibility to clindamycin can be determined by a standardized test method 2,4The MIC values obtained should be interpreted according to the criteria provided in Table 1.
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