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Prednisolone is mostly inactivated as it crosses the placenta, whereas betamethasone and dexamethasone cross readily.

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Nauseaheartburnheadachedizzinessmenstrual period changestrouble sleepingincreased sweatingor acne may occurIf any of these effects persist or worsentell your doctor or pharmacist promptly.

Take this medication by mouthwith food or milk to prevent stomach upsetexactly as directed by your doctorCarefully measure the dose using a special measuring device/spoonDo not use a household spoon because you may not get the correct dose.

Feverchillsa very sore throatear or sinus paina coughmore saliva or a change in colour of salivapain with passing urinemouth sores or a wound that will not healthese can be signs of an infection sleepy or confusedfeeling very thirsty or hungrypassing urine more oftenflushingbreathing quickly or breath that smells like fruitthese can be signs of high blood sugar weight gain in the upper back or bellymoon facevery bad headaches and slow wound healingthese can be signs of Cushing’s syndrome a very upset stomach or vomitingvery bad dizziness or passing outmuscle weaknessfeeling very tiredmood changesloss of appetite and weight lossthese can be signs of adrenal gland problems muscle pain or weaknessmuscle crampsor a heartbeat that does not feel normalthese can be signs of low potassium levels severe stomach painsevere back painsevere upset stomach or vomitingthese can be signs of pancreas problems.

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monitor patients for corticosteroid-related side effects if both prednisolone and itraconazole are taken.

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