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Physicians should exercise caution in monitoring the effects of XELODA in the elderlyInsufficient data are available to provide a dosage recommendation.

Whether you have a full or empty stomach can affect how much of a drug gets into your bloodstream.

Patients with moderate renal impairment at baseline require dose reductionsee DOSAGE AND ADMINISTRATIONPatients with mild and moderate renal impairment at baseline should be carefully monitored for adverse reactionsPrompt interruption of therapy with subsequent dose adjustments is recommended if a patient develops a grade 2 to 4 adverse event as outlined in Table 2see DOSAGE AND ADMINISTRATIONUse in Specific Populationsand CLINICAL PHARMACOLOGY

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