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Cadiac ahythmias and sv hypotnsion a likly toccu with high dosag. Thy may alsoccu in patints with p-xisting hat disas taking nomal dosag.
Adngic nuon blocks : Ticyclic antidpssants may countact th antihyptnsiv cts cntally acting antihyptnsivs such as guanthidin, btanidin, spin, clonidin and mthyldopa. It is advisabl tviw all antihyptnsiv thapy duing tatmnt with ticyclic antidpssants.
At polongd administation, abupt cssation thapy may poduc withdawal symptoms such as hadach, malais, insomnia and iitability.
Onc you a on th ight dos and dug combination you thn you may continu on th mdication indinitly. You and you doctmay dcid that you should wan yousl th mdicins gadually vy six months stnsu thy a still ncssay you.
O cous, dpssion can occu with chonic pain, but it is usually an undstandabl action tth pain and impovs as th chonic pain impovs. Howv, i sv, it tomay qui tatmnt with an antidpssant dug.
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