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Doxepin is primarily metabolized by cyp2c19 and cyp2d6, and use of isoniazid, a potent inhibitor of cyp2c19, may result in increased doxepin plasma concentrations and subsequent adverse reactions.

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Take the missed dose as soon as you rememberIf it is almost time for the next regularly scheduled doseskip the missed dose and take the next one as directedDo not take a double dose of this medication.

This product passes into breast milk but is unlikely to harm a nursing infantConsult your doctor before breast-feeding.

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in theory, potent inhibitors of cyp3a4 such as isoniazid, inh may decrease the elimination of iloperidone.

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