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The combination of ZETIA and atorvastatin or simvastatin is indicated for the reduction of elevated total-C and LDL-C levels in patients with HoFHas an adjunct to other lipid-lowering treatmentse.gLDL apheresisor if such treatments are unavailable.

Because clinical studies are conducted under widely varying conditionsadverse reaction rates observed in the clinical studies of a drug cannot be directly compared to rates in the clinical studies of another drug and may not reflect the rates observed in clinical practice.

If you have an allergy to ezetimibe or any other part of ZetiaezetimibeIf you are allergic to any drugs like this oneany other drugsfoodsor other substancesTell your doctor about the allergy and what signs you hadlike rashhivesitchingshortness of breathwheezingcoughswelling of facelipstongueor throator any other signsIf you have liver disease or raised liver enzymesIf you are pregnantIf you are breast-feeding or plan to breast-feed.

EzetimibeZetiais distinct from these agents because it does not inhibit cholesterol synthesis in the liver or increase bile acid excretionIt belongs to a class of lipid-lowering compounds that selectively inhibits the intestinal absorption of cholesterol and related phytosterolsEzetimibe’s pharmacological effect is complementary to that of the statins1

ZETIAadded to on-going statin therapysignificantly lowered total-CLDL-CApo Bnon-HDL-Cand TGand increased HDL-C compared with a statin administered alonesee Table 7LDL-C reductions induced by ZETIA were generally consistent across all statins.

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zetia is also known as ezetimibe, ezetrol.

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